Abstract
Thymoma is the most common neoplasm of the anterior mediastinum. Patients may be asymptomatic or present with symptoms of local compression, myasthenia gravis or other paraneoplastic syndrome. We present case of a middle aged woman with a large pleural based mass who was relatively asymptomatic Biopsy of the mass revealed thymoma type AB.Work up showed that she has multiple abdominal masses etiology of which is not known. Whenever feasible, surgery is the treatment of choice for thymoma.Our patient is undergoing chemotherapy with the goal that once the tumor size is reduced she will be able to undergo surgery.
Highlights
Thymoma is the most common neoplasm of the anterior mediastinum
We present case of a middle aged woman with a large pleural based mass who was relatively asymptomatic Biopsy of the mass revealed thymoma type AB.Work up showed that she has multiple abdominal masses etiology of which is not known
The thymus gland is located behind the sternum in front of the great vessels; it reaches its maximum weight at puberty and undergoes involution thereafter
Summary
The thymus gland is located behind the sternum in front of the great vessels; it reaches its maximum weight at puberty and undergoes involution thereafter. Precursor cells migrate to the thymus and differentiate into lymphocytes. The most common neoplasm of the anterior mediastinum, originates within the epithelial cells of the thymus. It accounts for 20-25% of all mediastinal tumors and 50% of anterior mediastinal masses .The etiology of thymoma is not clear; it has been associated with various systemic syndromes. CT scanning with intravenous contrast dye is preferred to show the relationship between the thymoma and surrounding vascular structures to define the degree of its vascularity and to guide the surgeon in removal of a large tumor, possibly involving other mediastinal structures. Stage III and IV and Recurrent Disease- Complete surgical removal of the tumor, if possible radiation after surgery (Table 1)
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