Ectopic Salivary Duct on the Lip Vermillion Border Having Arisen Congenitally from a Rhabdomyomatous Hamartoma in the Lower Labial Submucosa

Abstract

Rhabdomyomatous mesenchymal hamartoma (RMH) is a rare congenital lesion occurring predominantly in the skin, particularly of the face and neck. 1 Magro G. Di Benedetto A. Sanges G. et al. Rhabdomyomatous mesenchymal hamartoma of oral cavity: An unusual location for such a rare lesion. Virchows Arch. 2005; 446: 346 Crossref PubMed Scopus (28) Google Scholar The etiology of RMH is still unknown; possible explanations include aberrancy in the embryonic migration of mesodermally derived tissues or a genetic defect predisposing to the formation of this abnormality. 2 Rosenberg A.S. Kirk J. Morgan M.B. Rhabdomyomatous mesenchymal hamartoma: An unusual dermal entity with a report of two cases and a review of the literature. J Cutan Pathol. 2002; 29: 238 Crossref PubMed Scopus (62) Google Scholar Oral mucosa involvement in RMH is exceedingly rare, with only a few cases reported in the English-language literature. 1 Magro G. Di Benedetto A. Sanges G. et al. Rhabdomyomatous mesenchymal hamartoma of oral cavity: An unusual location for such a rare lesion. Virchows Arch. 2005; 446: 346 Crossref PubMed Scopus (28) Google Scholar , 2 Rosenberg A.S. Kirk J. Morgan M.B. Rhabdomyomatous mesenchymal hamartoma: An unusual dermal entity with a report of two cases and a review of the literature. J Cutan Pathol. 2002; 29: 238 Crossref PubMed Scopus (62) Google Scholar , 3 De la Sotta P. Salomone C. González S. Rhabdomyomatous (mesenchymal) hamartoma of the tongue: Report of a case. J Oral Pathol Med. 2007; 36: 58 Crossref PubMed Scopus (32) Google Scholar