Ectopic pregnancy efficacy of drug treatment

Abstract

Objective To find a simple, effective, high rate of success of small toxicity without affecting the reproductive function of drug treatment of ectopic pregnancy. Methods Two hundred and forty-nine cases of hospital patients with ectopic pregnancy, in which 136 treated conservatively. According to medication were randomly divided into group A (46 cases): methotrexate (MTX) 50 mg/ml single intramuscular injection and oral administration of mifepristone (Ru486);Group B (45 cases): MTX single intramuscular injection (50 mg/ml);Group C (45 cases): Mifepristone. regular monitoring of serum β-HCG levels and vaginal mass of B-monitored. Results The cure rate in group A was 97.8%,in group B was 86.7%, in group C was 88.9%. There was significantly reduced serum β-HCG dropped to normal time required to reduce the hospital stay in group A than that in group B,C(P 0.05). Conclusions The combination therapy with methotrexate and mifepristone treatment of ectopic pregnancy reduced the single dose, with high efficacy, short duration of side effects of the merits and is worth clinical application. Key words: Ectopic pregnancy ; Drug therapy ;