Ectopic meningioma in a patient with neurofibromatosis Type 2: a case report and review of the literature.

Chun Qiu Su,Mao Dong Zhou,Shan Shan Lu,Xun Ning Hong

doi:10.1259/bjrcr.20180007

Abstract

Ectopic meningioma occurring in the region of parapharyngeal space is rare in clinical practice and brings great challenge in its diagnosis. This report details such a case in a 14-year-old girl with neurofibromatosis Type 2, which is a highly infrequent association. The clinical manifestations, imaging findings, and pathological manifestations are described, and the relevant literature is reviewed to highlight characteristic imaging findings of ectopic meningiomas.

Highlights

Neurofibromatosis Type 2 (NF2) is a genetic neoplastic disorder that presents with multiple meningiomas and bilateral vestibular schwannomas,[7,8] and most meningiomas associated with NF2 arise intracranially
In view of the Haematoxylin and eosin (H-E) staining and immunohistochemical findings, the tumour was diagnosed as a benign ectopic meningioma of World Health Organization Grade I based on the 2007 World Health Organization classification.[9]
It has been suggested that primary ectopic meningiomas of the head and neck are related to neurofibromatosis, NF2

Summary

Introduction

Meningiomas are among the most common tumours of the central nervous system, accounting for nearly 20% of primary intracranial tumours.[1]. We report the clinical signs, imaging findings, and pathological manifestations of a rare case of meningioma occupying the parapharyngeal space in a patient with NF2. CASE REPORT Our patient, a 14-year-old girl, presented with a 4 month history of a painless mass in the right retroauricular area; it was first found in June 2015.

Results

Conclusion