Abstract

BackgroundIn France, 2–15% of the population is affected annually by influenza, which causes significant socioeconomic disruption. Nevertheless, despite its importance for policy makers, few published studies have evaluated the impact of influenza B. Therefore, we assessed the costs associated with influenza B during 2010–2011 in France.MethodsCases of lab-confirmed influenza B were analyzed as part of the Influenza B in General Practice Study. Cost calculations were based on micro-costing methods according to the French Health Insurance (FHI) perspective (in Euros, 2011). Costs were compared between age groups using the Kruskal–Wallis test, and when significant, by multiple comparisons based on rank. Moreover, uncertainties were assessed using one-way sensitivity and probabilistic analyses. Overall economic burden was estimated by multiplying cost per patient, flu attack rate, and the French population.ResultsA total of 201 patients were included in the study. We found that the mean cost associated with Influenza B was 72€ (SD: 205) per patient: 70€ (SD: 262) for younger children, 50€ (SD: 195) for older children, 126€ (SD: 180) for adults, and 42€ (SD: 18) for elderly. Thus, we observed significantly different costs between the distinct age groups (p<0.0001). Finally, the economic burden of influenza B for the FHI was estimated to be 145 million Euros (95% CI: 88–201).ConclusionsOur findings highlight the important impact of influenza B and encourage further investigation on policy regarding vaccination strategies in France.

Highlights

  • In France, 2–15% of the population is affected annually by influenza, which causes significant socioeconomic disruption

  • Our objective was to describe the costs associated with seasonal influenza B during the 2010–2011 season for a population presenting with acute respiratory infections (ARIs), consulting in primary care, under the perspective of the French Health Insurance (Assurance Maladie)

  • Study population Patient inclusion During the 2010–2011 flu season in France we observed an outbreak of flu B/Victoria and A(H1N1)pdm09 viruses

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Summary

Introduction

In France, 2–15% of the population is affected annually by influenza, which causes significant socioeconomic disruption. It is estimated that 5–15% of the world population is affected by acute respiratory infections (ARIs) [1]. In France, during the 2010–2011 influenza season, the incidence of primary care medical consultations for lab confirmed flu was estimated to be 6.7% (6710/100,000; 95% CI: 4411–9009). This figure represented a typical attack rate in a medium. Influenza viruses circulate during winter months (November–February in Europe), and epidemics last 8 weeks (on average) [4,5]. In some seasons, there may be two or three different dominant viruses [6]

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