Abstract

BackgroundMigraine is a primary headache disorder which affects all aspects of life. The financial burden of migraine imposed on the society might be substantial. This study aims at estimating the economic cost of migraine in Latvia and Lithuania, including both direct and indirect costs. Direct costs encompass the costs of migraine-related health care resource utilization. Indirect costs are related to productivity loss, the potential or expected earnings lost due to migraine.MethodsDirect cost is assessed by using the prevalence method, a widely used cost-of-illness approach. The prevalence rate of migraine and the migraine-related health care resource utilization are proxied from the literature, whereas unit cost of medical services and procedures are retrieved from national databases and providers. For estimating the indirect cost of migraine, we follow the human capital approach. We quantify three components of indirect costs: reduced labour force participation, absence from work and reduced productivity while at work. The number of unemployed migraineurs, days missed from work and days lost due to impairment while at work are drawn from the literature. Unemployment rate and average income in Latvia and Lithuania are then inserted to assess indirect costs.ResultsWe find that the mean per-person total cost of migraine is €801 annually in Latvia, and €721 in Lithuania. In both countries around 30% of total cost is direct cost; cost related to a wide array of migraine-related medical services and interventions. The total cost of migraine is €112.26 million in Latvia, corresponding to 0.42% of Latvia’s GDP. The total cost of migraine is €149.62 million in Lithuania, corresponding to 0.35% of Lithuania’s GDP. In both countries two thirds of total cost is related to lost workdays due to absenteeism and presenteeism.ConclusionsThe financial burden of migraine imposed on the society is substantial in Latvia and Lithuania. Improvements in care for patients with migraine, such as easier access to structured headache assessment services, wider availability of various procedures and preventive medications would significantly increase direct costs. Nevertheless, this cost increase might be far outweighed by lower migraine-related productivity loss, especially as the prevalence of migraine is the highest in the most productive years of life.

Highlights

  • Migraine is a primary headache disorder which affects all aspects of life

  • In this study we delivered a conservative estimate for the economic cost of migraine in Latvia and Lithuania; the prevalence rate of migraine and the number of lost workdays adopted from the literature can be considered as lower bounds for those items

  • We found that mean per-person total cost of migraine is €801 annually in Latvia, and €721 in Lithuania

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Summary

Introduction

Migraine is a primary headache disorder which affects all aspects of life. This study aims at estimating the economic cost of migraine in Latvia and Lithuania, including both direct and indirect costs. Direct costs encompass the costs of migraine-related health care resource utilization. Indirect costs are related to productivity loss, the potential or expected earnings lost due to migraine. Migraine sufferers use health care resources more often than individuals without migraine; they visit their general practitioners more frequently, they typically consult a neurologist about their headaches and several diagnostic tests are performed to rule out other causes of migraine symptoms. Costs associated with migraine-related health care resource utilization are labelled as direct costs. As migraine prevalence typically peaks between the ages of 25 and 55, during the most productive years of a person’s life, productivity loss is of particular importance [4]. Several recent studies report that direct costs are relatively low in comparison with indirect costs [5,6,7,8]

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