Abstract
The TN STEMI Program was a multicenter, prospective, observational study conducted in Tamil Nadu, India, that assessed the effects of implementing the STEMI India Model for the management of STEMI. We discuss the economic and societal impact in this article. Given that the intervention resulted in an absolute mortality reduction of 3.4%, we calculated a number needed to treat of 30 patients. At an annualized project cost of INR 15.11 million, this approximately calculates to INR 193,749 (USD 3,311) per life saved. The utility of the TN-STEMI Program can be estimated to be 1,108 life-years. This calculates to approximately INR 13,643 (USD 233) per life-year saved. Our estimates will likely be of particular interest to policy makers in low and middle-income countries, where financial and resource constraints pose a perennial public health challenge.
Highlights
The TN STEMI Program was a multicenter, prospective, observational study conducted in Tamil Nadu, India, that assessed the effects of implementing the STEMI India Model for the management of STEMI
Its burden is rising disproportionately among lower- and middle-income countries (LMICs) and populations; it is estimated that 80% of all cardiovascular deaths occur in LMICs [1, 2]
A lot of the mortality and morbidity from STEMI could be prevented if well-established therapies were made readily and uniformly available. This is challenging in LMICs due to significant limitations in human and financial resources
Summary
The average life-expectancy in Tamil Nadu in 2010–14 was 72.7 years for women and 68.6 years for men [12]. We can estimate the societal benefits even better from a productivity standpoint when we extrapolate this mortality difference in terms of net gain to the total economy due to the deaths averted This can be considered as the sum of net present value of all future income of the patients at the instance of their index event [13]. I = (GDP i s )/w where s is labour share of GDP w is total number of employed workers (income that did not happen because of death) from the pre-implementation period to the post-implementation period is the gain to the economy provided by the intervention. Annualising these numbers for 2,265 patients results in INR 228.7 million (USD 3.91 million) lost preimplementation and INR 175.6 million (USD 3 million) lost post-implementation, which is INR 53.1 million (USD 908,000) gained in the economy due to the protocol
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