Abstract
A general mild and efficient protocol for the synthesis of amidochloroalkylnaphthol libraries was achieved utilizing SiO2–ZnCl2 (silzic) as a reusable heterogeneous catalyst via Ritter-type reaction, through one-pot, three-component condensation of various aldehydes, chloroacetonitrile, and β-naphthol under solvent-free reaction conditions. The amidochloroalkylnaphthols were cyclized to its related oxazepinones, and their anticancer and antioxidant activities were studied.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.