Abstract

The development of a nanomaterials production process that is both economical and environmentally friendly is a result of the growing importance placed on people’s health. The Zinc oxide (ZnO)-Pluronic F127 (PF127)-Curcumin (CUR) nanoparticles (NPs) were synthesized through a green method using Senna auriculata flower extracts. These NPs were characterized using a variety of techniques, such as ultraviolet–visible spectroscopy (UV), Fourier transform infrared spectroscopy (FTIR), Field emission scanning electron microscopy (FESEM), Energy Dispersive X-ray analysis (EDAX), X-ray diffraction (XRD), photoluminescence (PL), and dynamic light scattering (DLS). From the XRD studies, synthesized ZnO-PF127-CUR NPs exhibit a wurtzite hexagonal crystal structure. The antimicrobial activity of ZnO-PF127-CUR NPs and Amoxicillin was tested against Staphylococcus aureus, Klebsiella pneumoniae, Shigella dysenteriae, Staphylococcus pneumoniae, Bacillus subtilis, proteus vulgaris, and candida albicans, respectively. The anticancer activity of ZnO-PF127-CUR NPs was tested against human breast cancer cell line (MDA-MB-237), and ZnO-PF127-CUR exhibits potential anticancer activity. These results support using ZnO-PF127-CUR NPs in healthcare manufacturing environments to improve human health.

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