Echoendoscopy-guided drainage of pancreatic collections using self-expanding metallic prosthesis: a retrospective observational cross-sectional study

Abstract

Background: Pancreatic fluid collections are local complications of acute pancreatitis. Advances in research and the development of new techniques to address local complications have allowed minimally invasive therapeutic options. Endoscopic ultrasound-guided drainage is currently the procedure of choice. Objective: To describe the results of the placement of a self-expanding metallic prosthesis for echoendoscopy-guided drainage of pancreatic collections in patients. Methods: This study followed a retrospective observational cross-sectional model (STROBE rules). The study was sent and approved by the Institutional Ethics Committee of the Federal University of the State of Rio de Janeiro, Brazil. For data analysis, descriptive statistical analysis (mean and standard deviation), non-parametric analysis (Kruskal-Wallis, with p<0.05 with a statistical difference in CI95%), and parametric analysis (One-Way Anova, with p>0.05 with a statistical difference in CI95%), and logistic regression analysis, with p<0.05 with statistical significance in CI95%. Results: Thirteen patients were referred for drainage of collections, and 4 patients were excluded. Of the 9 patients studied, there was a predominance of males (7:2) with a mean age of 54.5 years. Eight patients had walled-off necrosis (WON). The device used was the Hot AxiosTM self-expanding luminal apposition metallic prosthesis, which was inserted uneventfully in all patients. Complete resolution of the condition was found in 88.8% of cases. After logistic regression analysis between the categorical predictors (Gender and Age) versus the response predictors (Necrosectomy, Review Interval, and Stent Permanence), it was observed that certain Gender or Age can influence the response predictors. Conclusion: Drainage of pancreatic collections using minimally invasive techniques is a safe and effective procedure.