Abstract
Objective. To analyze heart rhythm variability, hemodinamics, pro- and anti-inflammatory plasma cytokines production in pregnant women. General clinical examination was carried out in both groups, echocardiography, Holter monitoring with subsequent calculation of generally accepted heart rate variability indices were performed. The circadian heart rate index (ratio day/night) was calculated. It was found that pregnancy-induced hypertension was accompanied by impaired cytokine balance. Altered immune homeostasis has been established to be a leading factor in the pattern of gestational complications.
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