Abstract
Introduction: Cardiomyopathies represent a heterogeneous group of diseases that often lead to progressive heart failure with significant morbidity and mortality. Exact epidemiological data on cardiomyopathy in Nepal are lacking. This study was done to observe the demographic and echocardiographic profile of patients with cardiomyopathy attending a medical college teaching hospital.
 Methods: Trans-thoracic two-dimensional echocardiographic study was performed by first author on all patients with cardiomyopathy over a period of six months. Patients’ demographic and echocardiographic data were collected and analyzed using SPSS version 20 software. Student t-test and Chi-square test were applied where appropriate.
 Results: A total of 60 patients were studied from October 2017 to March 2018. Mean age of all participants was 56.38 years (SD = 13.86). Mean age of males was significantly higher than that of females (60.96 yrs, SD = 13.61 versus 51.62 yrs, SD = 13.47) in dilated cardiomyopathy subgroup (p < 0.05). Of all patients, 32 (53.33%) had dilated cardiomyopathy (idiopathic) and 13 (21.66%) had ischemic cardiomyopathy.
 Conclusion: Our study highlighted significant burden of dilated cardiomyopathy. Dilated cardiomyopathy appeared in females at earlier age compared to males. Potentially reversible cardiomyopathies like alcoholic and peripartum cardiomyopathies were also present which have a probability of cure if treated properly.
Highlights
Cardiomyopathies represent a heterogeneous group of diseases that often lead to progressive heart failure with significant morbidity and mortality
Cardiomyopathies either are confined to the heart or are part of systemic disease conditions often leading to progressive heart failure.[2]
Dilated Cardiomyopathy (DCM) was labeled if enlarged left ventricle with decreased systolic function was present as measured by left ventricular ejection fraction (LVEF); excluding ischemic, valvular, hypertensive or congenital causes
Summary
Cardiomyopathies represent a heterogeneous group of diseases that often lead to progressive heart failure with significant morbidity and mortality. Cardiomyopathy is a heterogeneous group of myocardial disorders associated with mechanical and/or electrical dysfunction that causes abnormal myocardial performance.[1] Cardiomyopathies either are confined to the heart or are part of systemic disease conditions often leading to progressive heart failure.[2] Within this broad definition, cardiomyopathies usually are associated with failure of myocardial performance, which may be mechanical or electrical prone to life-threatening arrhythmias. The secondary cardiomyopathies are those associated with known cardiac or systemic processes These are referred to as specific cardiomyopathies named for the disease process with which they are associated.[5] Dilated Cardiomyopathy (DCM) is considered to be an important cause of heart failure and accounts for up to 25% of all cases of congestive heart failure (CHF). Dilated Cardiomyopathy (DCM) is considered to be an important cause of heart failure and accounts for up to 25% of all cases of congestive heart failure (CHF). [6] Out of all these, DCM is the most common form
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