Abstract
The aim of this paper was to report a case of a female Rottweiler dog, 9 years old, presenting eccentrocytes in blood caused by the presence of a lipoma. This morphological change in red blood cells is considered uncommon, especially when related to cancer. The blood count revealed the presence of eccentrocytes, while the fine-needle aspiration cytology and histopathology of the nodule revealed to be a lipoma. Pre-surgical tests showed high levels of lipid peroxidation in the bloodstream, a parameter for assessment of oxidative stress, and increased antioxidant enzymes. Ten days after removal of the neoplasm, the values of lipid peroxidation and antioxidant enzymes decreased. One month after the surgery, there were no eccentrocytes in blood circulation. Thus, it appears that the occurrence of eccentrocytes in this case is linked to the presence of lipoma, which leads to an increase in lipid peroxidation and in antioxidant enzymes activities.
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