Abstract
Zoie immune system including innate immunity and adaptive immunity.Innate immune system is a general defense mechanism which is built up in the process of development and evolution of biological spe-cies,including tissue barrier function,cell-mediated immunity,and humor immunity.Innate immunocytes ale activated by the recognition of mode elements on the pathogen.The immunological effect is producedthronsh special signal transduction pathway:Earthworm belongs to invertebrate whose immune system lacks immunoglobulin and has not developed adaptive immunity.So earthworm protects itself tllrough innate immu-nity. Key words: Earthworm; Innate immunity; Nuelease
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