Abstract

Objective: In cesarean section (CS), which, early vs. delayed cord clamping is better for neonatal and maternal hematocrit/hemoglobin level is not yet completely determined. This randomized controlled study attempted to determine this issue. Methods: Study population consisted of 64 full-term pregnant women/neonates undergoing planned CS: 32 received early cord clamping (ECC: 15 seconds after birth) and 32 delayed cord clamping (DCC: 90 seconds). We measured and analyzed 1) neonatal hematocrit at the first 24 - 48 hours, and 2) maternal-hemoglobin-change before and after CS. Results: Infants with ECC and DCC showed hematocrit (24 - 48 hours) of 57.47 ± 8.65 vs. 59.54 ± 7.67, showing no significant difference. Also, no significant differences were observed in the change in maternal hemoglobin in two groups. Conclusions: Cord clamping at 15 vs. 90 seconds did not yield neonatal hematocrit change or maternal hemoglobin change. As far as the present data (neonatal and maternal anemia) was concerned, cord may be clamped at 15 seconds in planned term CS.

Highlights

  • We here attempted to determine the neonate hematocrit value between the first 24 - 48 hours of life of the newborn and change in maternal hemoglobin, comparing ECC (15 s) versus DCC (90 s), during elective cesarean sections performed at the Obstetrics Department of the Complejo Hospitalario CSS, in Panama City, Panama

  • A total of 64 patients were included in the study, randomly admitted, who met the inclusion criteria, who were interested in participating in the study and signed the informed consent

  • The ∆ maternal hemoglobin in the ECC arm resulted in 1.17 ± 0.76, and in the DCC arm resulted in 1.0 ± 0.75, without achieving statistical significance (p = 0.38). (Table 2)

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Summary

Introduction

It’s known that adequate placental transfusion reduces the risk of iron deficiency in the neonate and could increase iron storage in late childhood [1]-[6]. Which, early vs late cord clamping, is better for neonatal hematocrit level, is not yet completely determined. We here attempted to determine the neonate hematocrit value between the first 24 - 48 hours of life of the newborn and change in maternal hemoglobin, comparing ECC (15 s) versus DCC (90 s), during elective cesarean sections performed at the Obstetrics Department of the Complejo Hospitalario CSS, in Panama City, Panama

Trial Design
Participants
Procedure
Outcome Measures
Sample Size
Randomization
Data Collection
Statistical Analysis
Results
Discussion
Conclusion
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