Abstract

Neurodevelopment Prior to eye opening, neurons in the visual cortex of certain mammals respond to orientation of a visual stimulus but cannot parse its direction of motion. In the weeks after the eyes open, the visual cortex acquires this ability. Roy et al. studied the newborn ferret to determine how synaptic and cell-intrinsic properties enable the development of direction selectivity. Receptive fields of mature neurons were more elongated along the temporal axis and narrower along the space-time axis compared with the receptive fields for neurons before visual stimulus. With visual experience, neurons improved their short-latency responses but also became more selective in their responses. eLife 9 , e58509 (2020).

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