Abstract

Background Coronary artery disease (CAD) is an important cause of morbidity and mortality in women and requires early diagnosis for defining the appropriate treatment. Objective To identify the positive predictive value (PPV) and safety of the early use of handgrip exercise in pharmacological stress echocardiography using dobutamine (early-ECHO) in women. Methods Positive ischemic early-ECHO records from 111 women were evaluated from January 2012 to March 2018. Subsequently, the hospital medical records were verified to locate patients who underwent conventional [...]

Highlights

  • Ischemic heart disease is an important public health problem in Brazil

  • Early-ECHO showed a high positive predictive value (PPV) for diagnosing myocardial ischemia in women

  • This review showed that ECHO provided a sensitivity of 79% and a specificity of 83% when compared with conventional coronary angiography (CCA).[21]

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Summary

Introduction

Ischemic heart disease is an important public health problem in Brazil. Between 2008 and 2018, 488 858 deaths of women due to coronary artery disease (CAD) were reported.[1]. Clinical presentations of CAD result from atherosclerosis of the coronary arteries and overt angina syndromes, acute myocardial infarction, ischemic cardiomyopathy, and sudden cardiac death. Coronary artery disease (CAD) is an important cause of morbidity and mortality in women and requires early diagnosis for defining the appropriate treatment. Among patients with severe CAD, 16 (27.6%) underwent myocardial revascularization surgery; 34 (58.6%) underwent percutaneous coronary angioplasty; and 08 (13.7%) had their clinical treatments intensified. Conclusions: Early-ECHO showed a high PPV for diagnosing myocardial ischemia in women. It presented a low complication rate and provided rapid disease identification, allowing the early treatment of injuries and potentially preventing CAD complications.

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