Abstract

The study is aimed at assessing whether the early surgical intervention improves survival in acute mesenteric ischemia with septic shock. A retrospective study design was applied to review the charts of patients admitted to the intensive care unit. The data were collected through a review of the full patient chart including physician and nursing notes, pathology reports, intraoperative findings, CT findings, and endoscopy. The diagnosis of AMI for each patient was determined through clinical presentation/endoscopic visualization/laboratory results/radiographic imaging, surgical exam (tissue or visual) and/or autopsy. Death and survival were evaluated between short and long-time-interval for septic shock groups using the chi-square test followed by calculating the P value. Total survival among the surgery group was 60 patients (95.24%) compared to 3 (4.76%) survival among patients who did not have surgery. The time from the onset of a shock to the time of surgical incision was calculated. The mean time to surgery was 17.7 hours. Total 65 patients (29.52%) had surgery between 4 and 12 hours from the onset of hypotension. Survivals among this group of patients were 41.7% (n = 25). The survival difference was statistically significant than died patients with respect to the time of surgical intervention (P = <0.001). Early removal of ischemic bowel in patients with AII-related surgery has improved survival.

Highlights

  • Acute mesenteric ischemia (AMI) defines as the prevalence of a sudden cessation of the mesenteric blood flow with the progression of symptoms that may differ from minutes to hours in time of onset [1]

  • The diagnosis of AMI is usually complicated in critically ill patients, for nonocclusive mesenteric ischemia (NOMI)

  • The study has retrospectively reviewed the charts of 327 patients who were admitted to the intensive care unit (ICU) in 22 tertiary hospitals

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Summary

Introduction

Acute mesenteric ischemia (AMI) defines as the prevalence of a sudden cessation of the mesenteric blood flow with the progression of symptoms that may differ from minutes to hours in time of onset [1]. The survival rate has improved in patients with AMI. Surgical intervention including revascularization or bowel resection in patients with AII has improved survival [11]. The diagnosis of AMI is usually complicated in critically ill patients, for nonocclusive mesenteric ischemia (NOMI).

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