Abstract
A study of the initial phases of the aggregation of trypsin-dissociated embryonic neural retina reveals three major stages: (1) initial, apparently non-specific adhesions of the cells into small clusters with no definable organization; (2) orientation of cells; (3) formation of composite aggregates by accretion of the smaller cell clusters. The morphological polarity of cells is retained after dissociation but appears to play no discernible role in the location of the initial cell adhesions. Two hours after the onset of aggregation the cells within the clusters have become oriented with respect to each other in accordance with their original polarities to form concentric structures with the mitochondria-containing portion of the cell directed towards the center of the cluster. These concentric cell configurations are retained following the fusion of the small clusters into the larger, composite aggregates.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
