Early-stage Dupuytren's disease treatment; a promising next step?

Abstract

Dupuytren's disease is a common progressive fibrotic condition in which nodules in the palm of the hand and fingers can develop into fibrous cords. Over time, the fibrous cords can develop into flexion contractures, for which patients often seek treatment. The consensus is that Dupuytren's disease does not need treatment until contractures develop to greater than 30° at the metacarpophalangeal and 15° at the proximal interphalangeal joint.1 Treatment commonly consists of limited fasciectomy to remove the cord, needle aponeurotomy, or collagenase injection to weaken and break the cord.