Abstract

The amplitude of the early receptor potential (ERP) of the isolated frog retina decreases when the retinal visual pigments are bleached; however, the amplitude subsequently recovers in the dark to 80–90 per cent of that prior to bleaching. This recovery is completed in 10–15 minutes at 25°C and 20–25 minutes at 8°C, and is observed when white or monochromatic (380, 490, or 630 nm) test flashes are used. Little rhodopsin regenerates during this period of rapid ERP recovery, and the spectral sensitivity of the ERP peaks at about 560–590 nm. These results suggest that the ERP recording from the isolated frog retina is generated by cone pigments.

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