Abstract

BackgroundRemoval of immobilization is a critical phase of distal radius fracture (DRF) rehabilitation, typically occurring by 2 months post injury. This study examined the extent to which pain at rest (PAR), movement evoked pain (MEP), or the ratio between those (MEPR) assessed at 2-months after DRF predicts the occurrence of chronic pain or disability at 6- and 12-months after the injury.MethodsThis secondary analysis of a prospective cohort study was done at the Hand and Upper Limb Centre (HULC), London, Ontario, Canada. A total of 229 patients with DRF (159 (69.4%) women) were included. Scores for the pain and function subscales of the Patient-Rated Wrist Evaluation (PRWE) were extracted for 2, 6 and 12 months after DRF. Logistic as well as nonlinear quartile regression examined whether PAR and MEP predicted the severity of chronic pain and disability at 6- and 12-months after DRF. Receiver Operating Characteristics Curve were plotted, where area under the curve (AUC) examined the accuracy of the PAR and MEP scores in classifying those who experienced chronic pain and disability.ResultsScores of ≥3 (AUC of 0.77) for PAR or ≥ 6 (AUC of 0.78) for MEP at 2 months after DRF predicted moderate to severe wrist pain at 6-months, whereas scores of ≥7 (AUC of 0.79) for MEP at 2-months predicted ongoing wrist disability at 6-months after the injury. The MEPR of 2 ≤ or ≥ 8 at 2-months was associated with adverse pain at 6-months and functional outcomes at 6- and 12-months (R-square = 0.7 and 0.04 respectively), but prediction accuracy was very poor (AUC ≤ 0.50).ConclusionChronic wrist-related pain at 6-months can be predicted by either elevated PAR ≥ 3/10) or MEP (≥ 6/10) reported at 2-months after the injury, while disability experienced at 6-months after DRF is best predicted by MEP (≥7/10) reported at 2-months. The ratio of these two pain indicators increases assessment complexity and reduces classification accuracy.

Highlights

  • Chronic pain is a common and disabling consequence of musculoskeletal (MSK) conditions [1]

  • All the continuous variables satisfied the assumptions of normal distribution (p > 0.05), including pain at rest (PAR) and movement evoked pain (MEP), with MEPR being the only exception

  • There were no differences in the scores of PAR, MEP, or MEPR at 2-months, 6-months, or 12-months between men and women except for scores for PAR at 6-months where men reported higher pain compared to women (2.13 ± 2 for men vs. 1.76 ± 1.4; p < 0.003)

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Summary

Introduction

Chronic pain is a common and disabling consequence of musculoskeletal (MSK) conditions [1]. Movement evoked pain (MEP) reflects an assessment of pain intensity during movement, reflecting the extent to which pain is aggravated by movement. Both PAR and MEP are meaningful indices for patients and clinicians. Pain with movement may contribute to fear of movement and reduced activity levels For these reasons it might be theorized that MEP facilitates better understanding of functional disability in an individual with MSK injury and represents pain in context [2]. This study examined the extent to which pain at rest (PAR), movement evoked pain (MEP), or the ratio between those (MEPR) assessed at 2-months after DRF predicts the occurrence of chronic pain or disability at 6- and 12-months after the injury

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