Abstract
Spinal metastasis of neuro-endocrine tumours (NETs) usually arise from a primary in the lung. We encountered such a patient with NET metastasis to T6 vertebra causing severe cord compression. Considering the neurological status, immediate decompression surgery along with T3-T8 posterior stabilization was done. Early recurrence of the tumour causing near total obliteration of the spinal canal leading to significant neurological compromise was noted within one month of surgery. A second surgery at this stage was avoided due to the risk involved and concurrent chemo-radiotherapy was initiated. The tumour was sensitive to chemo-radiotherapy and rapid resolution was noted on subsequent follow-up visits. With appropriate rehabilitation, patient regained full power to become ambulant with support. This case report highlights a rare, early and aggressive recurrence of metastatic vertebral NET following index surgery which was effectively managed with chemo-radiotherapy.
Highlights
Case ReportA 45-years-old male engineer with no history of trauma, presented to us with progressive upper back pain for two months that eventually became severe and disabling
Introduction highlighted in this reportNeuro-endocrine tumours (NETs) arise from cancerous cells of the widely distributed endocrine system and are considered diverse [1]
We describe a case of newly diagnosed neuro-endocrine tumours (NETs), metastasizing from right lung to the T6 vertebra, causing severe cord compression demanding immediate decompression surgery
Summary
A 45-years-old male engineer with no history of trauma, presented to us with progressive upper back pain for two months that eventually became severe and disabling. Patient indicated altered sensation from T8 dermatome and below; upper and lower limb motor power was normal. One month after the index surgery, patient developed significant motor deficit in the lower limbs At the end of radiotherapy and four courses of chemotherapy (4 months post-op), there was significant clinical improvement of neurology and complete resolution of the soft tissue enhancement surrounding the spinal cord was evident in the MRI (Fig. 7). With appropriate physiotherapy and rehabilitation, patient gradually regained full power in both lower limbs by 6 months He continues to be under oncology follow up and is ambulant with support
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
