Abstract
The study was to observe the safety and anti-inflammatory effects of a topical herbal agent. The herbal patch contained extracts of the 3 herbs Flos carthami (c´ e± ), Radix dipsaci (coae·), Rhizoma rhei (a¤§e») and Borneolum syntheticum (a°c). The Pain score Visual Analogue Scale (VAS) and Foot Function index (FFI) questionnaires were conducted to measure pain and disability. Blood was taken to measure the inflammation cytokines. All the assessments were processed on before and after the treatment intervention. After treatment, the pain score and foot function index were remarkably improved. Inflammation Cytokine IL-8 was decreased. The novel herbal patch used in this study has laboratory evidences of anti-inflammation and pro-angiogenesis. With its mildly penetrative property, it could be a suitable additional tool for patients’ self-care.
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