Abstract
Materials and Methods: One hundred and twenty-one patients treated on a phase I/II dose escalation study underwent irradiation directed to the prostate and seminal vesicles. The clinical stage of these patients were as follows: TlC=2 (2%); T2A=5 (4%); T2B=20 (17%); T2C=41 (34%); T3A=17 (14%); T3B=2 (2%); T3C=33 (28%). All patients were treated with a 6 field conformal technique. Seventy-six patients received a prescription dose of 75.6 Gy to the target volume and 45 patients received 81 Gy. The median pretreatment PSA value was 15.4 ng/ml. Toxicity was scored according to the RTOG scheme. The median follow-up was 15 months.
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