Abstract

High rates of early mortality are a consistent feature of antiretroviral therapy (ART) rollout programs in Africa, despite otherwise impressive reductions in morbidity and mortality. Advanced HIV disease at treatment initiation (as reflected by low CD4-cell counts) is likely the cause of many of these deaths, but immune reconstitution inflammatory syndrome (IRIS) could also play a role. In the present study, investigators evaluated mortality rates and causes of death among 559 patients in urban Uganda (69% women) …

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