Early Life Rhinovirus Wheezing, Allergic Sensitization, and Asthma Risk at Adolescence

Abstract

FJ Rubner, DJ Jackson, MD Evans. J Allergy Clin Immunol. 2017;129(2):501–507 To define the relationships among specific viral illnesses and the type and timing of aeroallergen sensitization with the persistence of asthma into adolescence. This is a prospective cohort study that enrolled 289 newborns who had a parental history of respiratory allergies and/or asthma and were followed to age 13 years ( n = 213). After enrollment, the infants had scheduled visits at ages 2, 4, 6, 9, and 12 months and annually thereafter. They were also seen during periods of acute illness. At these visits, nasal lavage was collected and analyzed for respiratory viruses. The viral panel included RSV, RV, influenza types …