Abstract

Adult life expectancy has progressively increased over the past 150 years, equivalent to one year added per four years of historical time in high life-expectancy populations. This amazing decline of mortality at all adult ages is attributed to environmental and technological advances. Explanations of the decline in longter mortality typically are seated in terms of period or historical factors, to the neglect of cohort or life cycle factors. From associations between the early and later age mortality for birth cohorts, we argue that historical reduction in lifetime exposure to infectious diseases and other sources of inflammation is a major cause of the decline in old age mortality.

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