Abstract
Pauwels RA, Pedersen S, Busse WW, et al. Lancet . 2003;361:1071–1076 To determine whether treatment with low-dose inhaled budesonide would prevent severe asthma-related events and accelerated lung function decline among patients with recent-onset, mild, persistent asthma. A group of 7241 patients, 5 to 66 years of age, with mild asthma symptoms for 3 months to 2 years, were recruited from 499 sites in 32 countries. Patients were randomly allocated to receive 400 μg of budesonide (200 μg for patients <11 years …
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