Early Gastric Cancer: Current Advances of Endoscopic Diagnosis and Treatment.

Linlin Zhu,Tianjiao Guo,Jinlin Yang,Jin Wang,Jinyu Qin,Zijing Wang

doi:10.1155/2016/9638041

Abstract

Endoscopy is a major method for early gastric cancer screening because of its high detection rate, but its diagnostic accuracy depends heavily on the availability of endoscopic instruments. Many novel endoscopic techniques have been shown to increase the diagnostic yield of early gastric cancer. With the improved detection rate of EGC, the endoscopic treatment has become widespread due to advances in the instruments available and endoscopist's experience. The aim of this review is to summarize frequently-used endoscopic diagnosis and treatment in early gastric cancer (EGC).

Highlights

Gastric cancer is the fourth most common cancer worldwide and the second leading cause of cancer death [1]
As a class of minimally invasive endoscopic techniques, endoscopic submucosal dissection (ESD) is characterized by fewer traumas and complications and better therapeutic effects
This review aims to summarize frequently used endoscopic diagnosis and treatment methods in early gastric cancer (EGC), such as magnifying endoscopy with narrow-band imaging (MENBI), confocal laser endomicroscopy (CLE), endoscopic mucosal resection (EMR), and ESD

Summary

Introduction

Gastric cancer is the fourth most common cancer worldwide and the second leading cause of cancer death [1]. With the raised public awareness on early diagnosis and treatment of cancer as well as the development of endoscopic imaging and image enhanced techniques, such as magnification narrow-band imaging, chromoendoscopy, and confocal laser endomicroscopy, the proportion of early gastric cancer (EGC) at diagnosis is increasing. According to the PARIS classification of superficial neoplastic lesions in the digestive tract [5], type 0 is divided into three categories corresponding to protruding lesions (0-I), nonprotruding and nonexcavated lesions (0-II), and excavated lesions (0-III). Type 0-II is divided into three subtypes, a, b, and c, corresponding to slightly elevated, flat, and depressed lesions. Techniques of endoscopic treatment for early gastric cancer include endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD). ESD has been shown to increase en bloc resection of lesions regardless of their size, location, or presence of scarring [2, 6, 7]. As a class of minimally invasive endoscopic techniques, ESD is characterized by fewer traumas and complications and better therapeutic effects

Endoscopic Diagnosis

Conclusion

Findings

Conflict of Interests