Abstract

Background: Following lung transplantation (LT), long-term survival is hindered by the high rate of obliterative bronchiolitis (OB). One major risk factor for the development of OB is recurrent acute rejection (AR). No immunomodulatory regimen has been shown to be more effective than another halting the progression of OB. We report our experience with sirolimus (SIR) in LT pts with OB or recurrent AR.

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