Abstract
Aim: The aim of the study is to find out the role of common haematological parameters along with micro-ESR, I/T ratio in diagnosis of neonatal sepsis for initiating early management.Methods: This is a descriptive study consisting of 35 neonates admitted at a sophisticated institute with clinical suspicion of septicaemia along with 40 neonates as the comparison group. The neonatal haematological parameters including total leucocytes count, absolute neutrophil count, immature neutrophil count, I/T ratio, platelet count were measured in all the neonates. Micro-ESR was measured as a bed side test. CRP was also measured using slide agglutination method and the results were compared with turbidimetric method. Blood culture was done as a gold standard test for sepsis. Micro-ESR more than age of the patient in days +3 mm in 1st hour was considered significant for sepsis. I/T ratio more than or equal to 0.2 was considered positive for sepsis.Results: The study revealed that micro-ESR and I/T ratio were significantly higher (p<0.001) in suspected cases of septicaemia as compared to the neonates in the comparison group. Sensitivity and specificity of micro-ESR were 87.09% and 75.0% respectively. Sensitivity and specificity of I/T ratio were 93.54% and 95% respectively.Conclusion: Micro-ESR and I/T ratio can be used effectively as cheap and simple tests to screen for septicaemia in neonate which is possible even in a primary health care centre.Bangladesh Journal of Medical Science Vol.14(2) 2015 p.169-172
Highlights
Neonates are newborn child within first 28 days of life[1]
In this study we found that among 35 neonates suspected of sepsis, blood culture is positive in 13(42%) neonates
There was no significant difference between the Total leukocyte count (TLC) (p=0.326) and ANC (p=0.695) between the cases and comparison group
Summary
Neonates are newborn child within first 28 days of life[1]. Neonatal sepsis is a clinical syndrome characterized by signs and symptoms of infection with or without accompanying bacteraemia within neonatal period[2]. Diagnosis of neonatal sepsis in primary health care unit sometimes, patients are advised oral antibiotics on clinical suspicion of sepsis during outdoor visit before they get admitted or before taking blood samples for culture and the culture report is dubious . Studying the I/T ratio & micro-ESR may provide a simple, cost effective tool as a screening test for early diagnosis of neonatal sepsis.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
