Early diagnosis of infected acute necrotising pancreatitis

Abstract

The aim of the work: to determine criteria for early diagnosis of infected acute necrotising pancreatitis.
 Materials and Methods. The study was based on complex treatment of acute pancreatitis (AP) in 63 patients, who were divided into two groups: group I – with severe and critical AP (n=31) and group II – with light and medium severity rate of AP (n=32). All required laboratory and instrumental methods were made and some special, particularly the procalcitonin levels in the blood serum (group I). Determination of prognostic parameters was made through correlation analysis of all clinical parameters. The attention was paid to statistically significant factors that correlate ratio not lower than 0.7 (strong correlation).
 Results and Discussion. The level of procalcitonin in blood > 3.7 ng/ml in first study group was those factor that showed the risk of developing more severe stage of pancreatitis with complications. Procalcitonin should be used as a marker of infected acute necrotic pancreatitis (ANP) in combination with other parameters of inflammation, which helps to choose the correct treatment.