Abstract
Gall bladder carcinoma is the most common biliary tract cancer. Delayed presentation and early spread of tumor make it one of the lethal tumors with poor prognosis. Considering that simple cholecystectomy for T1 disease could offer a potential cure, it is increasingly needed to identify it at early stages. Identification of high-risk cases and offering prophylactic cholecystectomy can decrease the incidence of gallbladder carcinoma. With advances in diagnostic tools like contrast-enhanced endoscopic ultrasound, elastography, multidetctor CT, MRI, and PET scan, we can potentially diagnose gallbladder carcinoma at early stages. This paper reviews the various diagnostic modalities available and an algorithmic approach to early diagnosis of gallbladder carcinoma.
Highlights
Gallbladder carcinoma (GBC) is the most common biliary tract cancer, accounting for 3% of all tumors [1]
It becomes increasingly necessary for early diagnosis and identi ng patients at high-risk of carcinoma and offer them prophylactic cholecystectomy
Us, routine use elastography during ultrasonography to evaluate increased gallbladder wall thickness combined with multidetector row computed tomography (CT) (MDCT) and contrast-enhanced endoscopic ultrasound can help in early diagnosis and staging of diffuse wall thickening type of gallbladder carcinoma
Summary
Gallbladder carcinoma (GBC) is the most common biliary tract cancer, accounting for 3% of all tumors [1]. Considering that survival a er simple cholecystectomy for T1 disease is reported to be near 100% [3] It becomes increasingly necessary for early diagnosis and identi ng patients at high-risk of carcinoma and offer them prophylactic cholecystectomy. In Delhi, GBC (incidence rate 6.6) was the fourth most common cancer (following cervix, breast, and ovary; incidence rates being 30.1, 28.3, and 8.7, resp.) and the most common gastrointestinal cancer in women (commoner than oesophagus 4.6, stomach 2.4, and colon 2.0) [4] Risk factors for this neoplasm include gallstones and a history of chronic cholecystitis and an estimated 22% of patients with porcelain gallbladder will develop carcinoma. Gallbladder carcinoma may appear at any of these imaging techniques as a mass completely occupying or replacing the gallbladder lumen, focal or diffuse asymmetric gallbladder wall thickening, or an intraluminal polypoid lesion
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
