Early diagnosis of amanitin exposure (amatoxicosis) in a dog with a point‐of‐care diagnostic test

Abstract

To describe the rapid diagnosis, treatment, and clinical course of a dog that ingested an amanitin-containing mushroom. A 2-month-old female intact Australian Shepherd presented with diarrhea and vomiting, along with a possible mushroom exposure. Upon presentation, the dog's urine was collected and tested positive by a point-of-care rapid diagnostic test specific for detecting amanitins, the causative agents of amatoxicosis. This is the first reported case of amatoxicosis that was diagnosed using a point-of-care test prior to starting treatment. An early diagnosis helps to guide early treatment decisions in this frequently fatal toxicosis.