Abstract
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract and the stomach is the most affected site. Clinical manifestation is erratic depending on the tumor’s location, size, histological type, and stage. Ultrasound is useful in detecting gastric intramural tumor whereas computed tomography is the imaging modality of choice in further evaluating tumor characteristics and expansion, treatment planning, and monitoring recurrence. Definite diagnosis of GISTs is based on the immunohistochemical study. Early diagnosis and complete surgical resection of the tumor yield good long-term outcomes. We present a case of a small gastric GIST which was early detected and treated and the patient has tumor-free during 8 years of follow-up.
Highlights
Gastrointestinal stromal tumors (GISTs) represent a minority of the gastrointestinal malignancies but are the most common (80%-90%) mesenchymal subepithelial tumors of the gastrointestinal tract [1,2,3]
Intramural gastric tumors are typically mesenchymal in origin and include GISTs, non-GIST sarcomas, lipomas, leiomyomas, schwannomas, glomus tumors, hemangiomas, inflammatory fibroid polyps (IFPs), inflammatory myofibroblastic tumors (IMFTs), and plexiform fibromyxoma [3]
GISTs derive from a precursor of the interstitial cells of Cajal (ICC), normally present in the myenteric plexus in the muscular layer of the GI tract, and are clearly distinct from other mesenchymal tumors, such as leiomyoblastoma, leiomyomas or leiomyosarcomas [2,3,5]
Summary
Gastrointestinal stromal tumors (GISTs) represent a minority of the gastrointestinal malignancies but are the most common (80%-90%) mesenchymal subepithelial tumors of the gastrointestinal tract [1,2,3] These tumors occur most commonly in the stomach (60-70%), followed by the small intestine (20–30%), duodenum (4-5%), rectum (4-5%), colon (
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