Early diagnosis and prognosis of MINOCA by CMR

Abstract

Cardiovascular disease is a prevalent health concern in contemporary society. Numerous studies have indicated that certain individuals with myocardial infarction may not obtain symptoms of coronary obstruction in coronary angiography. As a result, there is a growing interest in exploring the evaluation of myocardial infarction with non-obstructive coronary arteries (MINOCA). This article focuses on the application of cardiovascular magnetic resonance (CMR) in the diagnosis and prognosis of MINOCA. In conjunction with the pathological characteristics of MINOCA and the imaging principles underlying CMR technology, this article investigates the role of CMR in the clinical practice of MINOCA. CMR is a valuable technique employed for studying multiple aspects of the heart, including morphology, function, organization and perfusion. By applying diverse parameters and sequences, this non-invasive imaging method emerges as an essential tool for clinical diagnosis and prognosis of various cardiovascular diseases. MINOCA is characterized by insufficient blood supply to the coronary arteries or direct myocardium dysfunction with non-ST-segment elevation and normal or less than 50% stenosis in angiography. The aetiology of MINOCA encompasses a wide range of factors, while the application of CMR shows ability to enhance the diagnostic sensitivity of MINOCA, enabling better identification of the underlying cause of the symptoms and facilitating a personalized prognosis for patients.