Abstract
Investigators at the Developmental Cognitive Neurosciences Unit, Institute of Child Health, London, other centers in the UK, and Dartmouth School of Medicine, NH, USA, prospectively recruited children aged between 1 and 42 months from North London who had at least one episode of convulsive status epilepticus (CSE) and classified them as prolonged febrile seizures (PFS) or nonfebrile CSE.
Highlights
An investigator from University of Oxford, UK, reviews the effect of sleep disorders on epilepsy and the effects of epilepsy on sleep
Following convulsive status epilepticus (CSE), children including those with prolonged febrile seizures (PFS) are developmentally delayed
The FEBSTAT Study Team investigated the association between FS duration and baseline characteristics of development in 158 children with a first FS, median duration 4 minutes (Hesdorffer DC, et al Ann Neurol 2011 Jul;70(1):93-100)
Summary
An investigator from University of Oxford, UK, reviews the effect of sleep disorders on epilepsy and the effects of epilepsy on sleep. Investigators at the Developmental Cognitive Neurosciences Unit, Institute of Child Health, London, other centers in the UK, and Dartmouth School of Medicine, NH, USA, prospectively recruited children aged between 1 and 42 months from North London who had at least one episode of convulsive status epilepticus (CSE) and classified them as prolonged febrile seizures (PFS) or nonfebrile CSE. Of 54 patients receiving neuropsychological and MR imaging tests within 6 weeks (mean 38 days) of CSE (baseline) and at 1-year follow-up, 27 had PFS (mean age 18.4 months) and 27 had nonfebrile CSE (mean age 15.5 months). Children with nonfebrile CSE had similar seizure characteristics but a worse developmental outcome than children with PFS (p
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