Abstract
Finding pancreatic cancer while it’s still curable with surgery remains one of oncology’s most frustrating challenges. A growing pancreatic tumor can take more than 15 years to metastasize, during which patients generally aren’t symptomatic. When they finally experience abdominal pain, weight loss, and other hallmarks of the disease, it’s usually too late: Pancreatic cancer almost always kills within 2 years of diagnosis. But research funding for pancreatic cancer is up from $17.3 million in 1999 to $96.5 million today, according to the Pancreatic Cancer Action Network in Manhattan Beach, Calif. Meanwhile, researchers are making steady progress in early detection, focusing on blood biomarkers that might reveal the illness noninvasively and imaging tools that reveal potentially curable precursor lesions. Between them, imaging has made much bigger gains, according to Teri Brentnall, M.D., a gastroenterologist and professor at the University
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