Abstract
P173 Aims Recent thrombolytic trials in acute stroke, and acute treatment in the USA, exclude patients with early CT changes of infarction affecting greater than one third of the middle cerebral artery (MCA) territory because of a possible increased risk of parenchymal haemorrhage. We reviewed CT scans of patients recruited into the Australian Streptokinase Trial to determine whether such changes or other factors were predictive in this group of patients. Methodology Acute CT scans were classified by three neurology research fellows according to ECASS criteria in 264 patients. Where consensus was not reached, a panel of ECASS trained physicians reviewed the scans. Haemorrhage on second CT were classified into haemorrhagic infarction or parenchymal haemorrhage. Results CT s showed no acute changes in 36%, minor ischaemic changes ( 1/3 MCA territory) in 35%. Major early ischaemic changes were predictive of haemorrhagic infarction (p=0.037) and stroke death (p=
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