Abstract

BackgroundBiliary-enteric anastomosis (BEA) is a common surgical procedure performed for the management of biliary obstruction or leakage that results from a variety of benign and malignant diseases. Complications following BEA are not rare. We aimed to determine the incidence and the factors associated with early complications occurring after BEA for benign diseases.MethodsWe reviewed the medical records of all patients who underwent BEA for benign diseases at our institution between January 1988 and December 2009. The primary outcome was early post operative complication. Logistic regression analysis was done to identify factors predicting the occurrence of complications.ResultsRecords of 79 patients were reviewed. There were 34 (43%) males and 45 (57% females). Majority (53%) had choledocholithiasis with impacted stone or distal stricture, followed by traumatic injury to the biliary system (33%). Thirty-four patients (43%) underwent a hepaticojejunostomy, 19 patients (24%) underwent a choledochojejunostomy, and choledochoduodenostomy was performed in 26 patients (33%). Early complications occurred in 39 (49%) patients - 41% had local complications and 25% had systemic complications. Most frequent complications were wound infection (23%) and bile leak (10%). Four (5%) patients died. On multivariate analysis, low serum albumin level (odds ratio = 16, 95% CI = 1.14-234.6) and higher ASA levels (odds ratio = 7, 95% CI: 1.22-33.34) were the independent factors predicting the early complications following BEA.ConclusionsHalf of the patients who underwent BEA for benign diseases had complications in our population. This high incidence may be explained by the high incidence of hypoalbuminemia and the high-risk group who underwent operation.

Highlights

  • Biliary-enteric anastomosis (BEA) is a common surgical procedure performed for the management of biliary obstruction or leakage that results from a variety of benign and malignant diseases

  • Biliary-enteric anastomosis (BEA) is a common surgical procedure performed for a variety of indications

  • Patient’s age, co-morbid conditions, nutritional status, pre-operative serum bilirubin, associated chronic liver disease, nature and extent of the primary disease and type of anastomosis performed have been proposed to influence the outcome of BEA [7,8]

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Summary

Introduction

Biliary-enteric anastomosis (BEA) is a common surgical procedure performed for the management of biliary obstruction or leakage that results from a variety of benign and malignant diseases. Biliary-enteric anastomosis (BEA) is a common surgical procedure performed for a variety of indications This includes bypass or reconstruction following resection of malignant or benign biliary obstruction, primary biliary stones, iatrogenic bile duct injury, liver transplantation; and a number of biliary tract problems that are benign but have malignant potential such as primary sclerosing cholangitis, choledochal cyst, and hepatolithiasis. Post-operative complications following BEA including anastomotic leak, hemorrhage, wound infection, cholangitis, intra-abdominal abscess/biloma and stricture formation have been reported [3,4,5]. These complications are sometimes serious enough to warrant a repeat surgery and at times result in serious long-term morbidity. We aimed to determine the incidence and factors associated with complications following BEA for a group of benign diseases

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