Early but not late insulin treatment improves left ventricular remodelling and cardiac function induced by myocardial infarction in rats

F Feng,W Jing,G Feng,J Lele,Y Weidong,Z Haifeng,L Wenchong

doi:10.1136/heartjnl-2011-300867.22

Early but not late insulin treatment improves left ventricular remodelling and cardiac function induced by myocardial infarction in rats

F Feng, W Jing + Show 5 more

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https://doi.org/10.1136/heartjnl-2011-300867.22

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Journal: Heart

Publication Date: Oct 1, 2011

Affiliation: Air Force Medical University

#Late Treatment #Interstitial Collagen Volume Fraction + Show 8 more

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Abstract

ObjectivesInsulin exerts significant cardioprotective effects in acute myocardial ischaemia/reperfusion (MI/R) through the PI3K-Akt signalling. The present study was aimed at investigating the effect of insulin treatment on the prolonged postischemic...

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