Early brain computed tomographic angiography to screen for blunt cerebrovascular injuries in patients with polytrauma: Is it necessary?

Abstract

Early diagnosis of blunt cerebrovascular injury (BCVI) is among the most difficult challenges in trauma treatment. This study aimed to determine the optimal timing of computed tomographic angiography (CTA) screening for suspicious BCVI in patients with polytrauma. We reviewed the trauma registry and medical records of patients with head and neck injuries from a Level I trauma center between January 2012 and December 2016. Those receiving CTA within 24h of presentation at the emergency department were the primary CTA group; those who received CTA after 24h were the delayed CTA group. The basic demographics, indications for CTA, CTA severity grading, and outcomes were compared. In all, 228 patients received brain CTA. Most were male (75%); the mean age was around 40years. The 38 patients with positive BCVI had a significantly higher ratio of severe chest trauma (52.6% vs 25.8%, p=0.001); 26 of them received primary CTA and 12 received delayed CTA. Patients with polytrauma predominated in the delayed CTA group (66.7% vs 30.8%, p=0.037). Of the patients in the primary CTA group, 26.9% received CTA due to symptomatic presentation (p=0.047). Patients in the delayed group had better neurological outcomes (83% neurologically intact, vs 38.5%, p=0.01) and lower mortality (0% vs 26.9%, p=0.047). The only independent positive prognostic factor was initial motor response ≥M5 (Odds Ratio 21.46, 95% Confidence Interval 2.01-228.71). For patients with polytrauma, performing brain CTA for BCVI screening in the first 24-h or after may not affect clinical outcome. Initial motor response is the sole indicator for outcome. Delaying the study for to the next 24-hour can be considered in such patients, when regarding hemodynamic stability, the dose of contrast medium, and the radiation exposure.