Abstract
Background The degree and quantification of contractile dysfunction and myocardial scar in patients after acute myocardial infarction (AMI) has important prognostic implications. Myocardial deformation parameters like strain and strain rate have been shown to be more sensitive markers for contractile dysfunction than standard 2-D parameters. We sought to investigate whether strain and strain rate imaging, assessed by a novel non-invasive post-processing feature tracking algorithm (FTI) on pre-acquired regular CMR SSFP images, would allow quantification of regional left ventricular (LV) function and its relation to degrees of infarct trans-murality in patients after AMI. Methods
Highlights
The degree and quantification of contractile dysfunction and myocardial scar in patients after acute myocardial infarction (AMI) has important prognostic implications
We sought to investigate whether strain and strain rate imaging, assessed by a novel non-invasive post-processing feature tracking algorithm (FTI) on pre-acquired regular Cardiac magnetic resonance (CMR) SSFP images, would allow quantification of regional left ventricular (LV) function and its relation to degrees of infarct trans-murality in patients after AMI
Cardiac magnetic resonance (CMR) imaging was performed on a 1.5T whole body MRI scanner (Philips Achieva) in 44 patients 3 ± 1 days after successfully reperfused first ST segment elevation AMI
Summary
The degree and quantification of contractile dysfunction and myocardial scar in patients after acute myocardial infarction (AMI) has important prognostic implications. Myocardial deformation parameters like strain and strain rate have been shown to be more sensitive markers for contractile dysfunction than standard 2-D parameters. We sought to investigate whether strain and strain rate imaging, assessed by a novel non-invasive post-processing feature tracking algorithm (FTI) on pre-acquired regular CMR SSFP images, would allow quantification of regional left ventricular (LV) function and its relation to degrees of infarct trans-murality in patients after AMI
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