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Abstract
Summary Sucrose gradient centrifugation and susceptibility to 2-mercaptoethanol were employed to identify γM and γG antibodies and to study the kinetics of antibody formation in mice injected with a single dose of emulsified influenza virus vaccine. Theoretical considerations based on the shapes of γM and γG response curves indicate that γM antibody was produced and subsequently catabolized at a faster rate than γG antibody. In addition, the mineral oil adjuvant increased production of γM and γG antibodies, although the effect on γG production was more striking.
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