Abstract

BackgroundWe report a case of hemorrhagic occlusive retinal vasculitis (HORV) after prophylactic intracameral vancomycin use during an uneventful cataract surgery treated with early anti-VEGF treatment.Case presentationA 51-year-old female underwent uneventful cataract surgery with prophylactic intracameral vancomycin during the procedure. On the seventh post-operative-day, she presented with sudden painful, visual loss. Fundus examination revealed peripheral hemorrhagic retinal vasculitis. She received anti-VEGF therapy to prevent further vision loss and retinal neovascularization due to extensive retinal ischemia. At the 6-month follow-up visit, visual acuity was 20/20 with no sign of neovascularization.ConclusionsPostoperative HORV is a devastating condition that can occur after otherwise uncomplicated cataract surgery. The nature of this rare condition remains unknown. Early anti-VEGF administration seems to demonstrate favorable results.

Highlights

  • We report a case of hemorrhagic occlusive retinal vasculitis (HORV) after prophylactic intracameral vancomycin use during an uneventful cataract surgery treated with early anti-Vascular Endothelial Growth Factor (VEGF) treatment.Case presentation: A 51-year-old female underwent uneventful cataract surgery with prophylactic intracameral vancomycin during the procedure

  • Postoperative HORV is a devastating condition that can occur after otherwise uncomplicated cataract surgery

  • We discussed our concerns with the patient and we proposed continuation of anti-VEGF for at least

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Summary

Conclusions

HORV is a devastating condition after otherwise uneventful cataract surgery. The early intervention with anti-VEGF treatment had a favorable result in restoring vision and preventing neovascularisation. It is difficult to draw accurate conclusions from single cases early anti-VEGF seems to have a positive role in stopping the cascade of HORV and preventing neovascularisation which if untreated would adversely affect patients vision and quality of life. Further studies are needed to ensure such a therapeutic effect

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