Ear nose throat manifestation of autoimmune blistering disorder

Abstract

Introduction: Autoimmune blistering diseases (AIBD) are rare blistering disorders of mucous membrane and skin caused by autoantibodies against specific cells. Ear, nose and throat (ENT) examination is must and should be a routine procedure to evaluate these patients for mucosal involvement as mucosal involvement significantly increases morbidity and mortality. These patients should be asked for oropharyngeal, ear, nose and throat symptoms and should be evaluated for the same by direct and endoscopic examination. Materials and Methods: 60 patients were taken in total, who had mucosal involvement. Ear, nose and throat (ENT) examination was done. Every case of mucosal involvement was promptly enquired about oropharyngeal, ear, nose and throat symptoms. All patients were clinically seen for ENT and dermatological manifestations by direct and endoscopic examination, cutaneous examination even in absence of symptoms. Result: Out of 60 patients, 42 were pemphigus vulgaris, 3 were pemphigus foliaceus, 8 were paraneoplastic pemphigus, 7 were mucous membrane pemphigoid. Conclusion: It is very important to evaluate every patient of mucosal lesion by both ENT and dermatologist for the better management of the patient to reduce mortality and morbidity.