(E)-1-(4-Aminophenyl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one

Abstract

Mol­ecules of the title amino­chalcone, C18H19NO4, are twisted, with a dihedral angle of 11.26 (6)° between the 4-amino­phenyl and 2,4,5-trimeth­oxy­phenyl rings. The conformations of the three meth­oxy groups with respect to the benzene ring are slightly different. Two meth­oxy groups are almost coplanar with the attached benzene ring [C—O—C—C torsion angles of −1.45 (19) and 1.5 (2)°], while the third is (−)-synclinal with the attached benzene ring [C—O—C—C = −81.36 (17)°]. In the crystal structure, mol­ecules are stacked into columns along the b axis and mol­ecules in adjacent columns are linked by N—H⋯O hydrogen bonds into V-shaped double columns. Weak π–π inter­actions are also observed, with a centroid-centroid distance of 3.7532 (8) Å.