Abstract
The purpose of our study was to visualize hemodynamics in a silicon vascular model with a middle cerebral aneurysm using Time-Resolved Three-Dimensional Phase-Contrast MR Imaging (4D-Flow). We created a realistic silicon model of a right middle cerebral artery bifurcation aneurysm. We ran an aqueous solution of glycerol as a flowing fluid through the silicon vessel model with a pulsatile pump. The 4D-Flow technique is based on a radiofrequency-spoiled gradient-echo sequence and it encodes flow velocity in three orthogonal directions. This technique was carried out using 1.5T MR scanner with a voxel size of 0.88x0.88x3mm, 20 phases during one cardiac cycle, and imaging time of 48min. Time-resolved images of three-dimensional streamlines clearly demonstrated that the aneurysm had three-dimensional complex vortex flows within it during systolic phase. A helical flow at the left aspect of the aneurysm was seen along the aneurysmal wall. The point where the helical flow reversed direction was coincident with the bleb. Flow rate of the bleb was low. In our model the 4D-Flow technique provided us with time-resolved three-dimensional hemodynamic information about the intracranial aneurysm and the adjacent parent artery.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
