Abstract

Dyslipidemia is highly prevalent among type 2 diabetic patients. It increases the risk of atherosclerosis and consequent mortality in diabetic patients. The aim of this study was to find out the prevalence of dyslipidemia among type 2 diabetic patients. This was a descriptive cross-sectional study in 355 type 2 diabetic patients at tertiary care hospital from 15th May, 2020 to 15th November, 2020 after taking ethical clearence from Institutional Review Committee (Reference no. IRC-PA-052/2077-78). Convenience sampling was done. Demographic and lipid profile variables were recorded based on the structured questionnaires. Data were analyzed by Statistical Package for the Social Sciences version 20. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data. Out of total 355 cases of type 2 Diabetes mellitus, prevalence of dyslipidemia was 224 (63.1%). It was more prevalent in male 145 (69.4%) than female 79 (54.1%). Increased Low density Lipoprotein (94.2%) was the most prevalent type followed by mixed dyslipidemia (91.1%). Dyslipidemia was common among type 2 diabetic patients and was higher in male gender, older age, obesity and longer duration of diabetes. Hence type 2 diabetic patient should undergo the routine monitoring of blood sugar and lipid profile so that any abnormalities can be identified and preventive measures along with interventions can be initiated at the earliest.

Highlights

  • Dyslipidemia is highly prevalent among type 2 diabetic patients

  • type 2 diabetes mellitus (T2DM) increases the risk of cardiovascular disease (CVD) several fold.[5]

  • Our study demonstrated higher prevalence of dyslipidemia among male than female i.e. 69.4% and 54.1% respectively which is comparable to similar study done at tertiary center in this region.[11]

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Summary

Introduction

Dyslipidemia is highly prevalent among type 2 diabetic patients. The aim of this study was to find out the prevalence of dyslipidemia among type 2 diabetic patients. In Nepal, prevalence of dyslipidemia is 63.8% in eastern, 61.0% in central and 90.7% in mid-western region.[3] Dyslipidemia is one of the important risk factor for vascular complications in diabetic patients. It increases free fatty acid flux secondary to insulin resistance and aggravated by increased inflammatory adipokine.[4] T2DM increases the risk of cardiovascular disease (CVD) several fold.[5]

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